Nose spray before surgery may ease behavior woes in kids with autism

NCT ID NCT07324057

First seen Jan 07, 2026 · Last updated May 08, 2026 · Updated 18 times

Summary

This study tests whether giving a sedative nose spray (dexmedetomidine or esketamine) before anesthesia can reduce negative behavior changes—like sleep problems, anxiety, or eating issues—in children with autism after surgery. About 234 children aged 2-12 will be randomly assigned to receive one of the two drugs or a saltwater spray. Researchers will track behavior changes for up to 28 days after surgery and monitor safety.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AUTISM SPECTRUM DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Nanjing Medical University

    RECRUITING

    Nanjing, Jiangsu, 210000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.