Could Pre-Exercise training boost strength in aging muscles?
NCT ID NCT07756762
First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time
Summary
This study tests whether an 8-week functional resistance training programme is practical and acceptable for older adults with probable sarcopenia—early muscle weakness that can affect mobility and independence. Participants will be randomly assigned to do the same exercises either in a supervised clinic setting or at home, with movements mimicking daily activities like standing and lifting. The main goal is to see if people will join, stick with, and safely complete the programme, while also exploring potential improvements in strength, physical function, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- An 8-week functional resistance training programme, delivered either supervised in a clinic or independently at home, focusing on everyday movements like standing, stepping, and lifting.
- What this could lead to
- If successful, this could pave the way for a gentle, pre-training step that helps older adults with early muscle weakness safely build strength and confidence, potentially improving mobility and quality of life.
- What could go wrong
- This is a small feasibility study, not a large trial, so results may not apply broadly. The programme's success depends on participants sticking with it, and it may not lead to significant physical improvements.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Aged ≥65 years 2. Confirmed at screening with probable sarcopenia according to EWGSOP2 criteria, defined as low muscle strength. 3. Community-dwelling, 4. Able to consent, 5. Able to demonstrate safe functional resistance training exercise technique assessed during pre-randomisation familiarisation session. Exclusion Criteria: 1. Diagnosed with Sarcopenia or severe sarcopenia (EWGSOP2) 2. Previous history of myocardial infarction within 12 months 3. Terminal illness, 4. Unstable cardiovascular disease 5. Uncontrolled hypertension 6. Cognitive impairment affecting consent 7. Recent major surgery 8. Pre-planned surgery in the next 12 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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