New pill aims to tame debilitating skin itch in major trial

NCT ID NCT06516965

Recruiting now Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an oral medication called povorcitinib can reduce severe, persistent itch and heal skin lesions in people with prurigo nodularis, a chronic skin condition. About 330 adults with moderate-to-severe disease will take either the drug or a placebo pill for 24 weeks to see which is more effective. The main goal is to see if the drug significantly improves itch and skin appearance compared to the placebo.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Aesthetic General Dermatology of Seattle
RECRUITING

Burien, Washington, 98168, United States
Akk Medical Sp. Z O.O. - Centrum Medyczne Tu Sie Leczy
RECRUITING

Gdansk, 80-280, Poland
Alergo-Med Osrodek Badan Klinicznych Sp. Z O.O.
WITHDRAWN

Tarnów, 33-100, Poland
Allcutis Research, Llc
COMPLETED

Portsmouth, New Hampshire, 03801, United States
Alpha Research-Lucere Dermatology and Laser Clinic
COMPLETED

Edmonton, Alberta, T6X 0N9, Canada
Aoi Dermatology Clinic
RECRUITING

Kumamoto, 861-2236, Japan
Area Sanitaria de Santiago de Compostela Y Barbanza - Complejo Hospitalario Universitario de Santiag
RECRUITING

Santiago de Compostela, 15706, Spain
Az Sint-Jan Brugge Av
RECRUITING

Bruges, 08000, Belgium
Broadgreen Hospital - Liverpool University Hospitals Nhs Foundation Trust
RECRUITING

Liverpool, L14 3LB, United Kingdom
Care Clinic Sp. Z O.O.
RECRUITING

Katowice, 40-568, Poland
Center For Clinical and Cosmetic Research
COMPLETED

Aventura, Florida, 33180, United States
Central Japan International Medical Center
RECRUITING

Minokamo, 505-8510, Japan
Central Sooner Research
RECRUITING

Oklahoma City, Oklahoma, 73118, United States
Centre Hospitalier Universitaire (Chu) de Liege - Domaine Universitaire Du Sart Tilman
RECRUITING

Liège, 04000, Belgium
Centre de Recherche Saint-Louis
RECRUITING

Québec, Quebec, G1W 4R4, Canada
Centro Internacional de Estudios Clinicos
RECRUITING

Santiago, 8420383, Chile
Centro Medico Skinmed Limitada
RECRUITING

Santiago, 7580206, Chile
Cityclinic Przychodnia Lekarsko-Psychologiczna Matusiak Spolka Partnerska
RECRUITING

Wroclaw, 50566, Poland
Clinical Research Center Spolka Z Ograniczona Odpowiedzialnoscia Medic-R Spolka Komandytowa
RECRUITING

Poznan, 61-731, Poland
Clinical Research Chile Spa.
RECRUITING

Valdivia, 5090000, Chile
Clinical Science Institute Clinical Research Specialists Inc
RECRUITING

Santa Monica, California, 90404, United States
Clintrial S.R.O.
RECRUITING

Prague, 100 00, Czechia
Dermatologische Gemeinschaftspraxis Dres. Quist
RECRUITING

Mainz, 55128, Germany
Dermatology Associates Pc
COMPLETED

Rockville, Maryland, 20850, United States
Dermatology Specialists Research
COMPLETED

Louisville, Kentucky, 40241, United States
Dermedic Jacek Zdybski
NOT_YET_RECRUITING

Ostrowiec Świętokrzyski, 27-400, Poland
Dermeffects
RECRUITING

London, Ontario, N6H 5L5, Canada
Dermoklinika Centrum Medyczne S.C., M. Kierstan, J. Narbutt, A. Lesiak
RECRUITING

Lodz, 90-436, Poland
Direct Helpers Research Center
RECRUITING

Hialeah, Florida, 33012, United States
Dokkyo Medical University Saitama Medical Center
RECRUITING

Minamikoshigaya, 343-8555, Japan
Drk Krankenhaus Chemnitz-Rabenstein
RECRUITING

Chemnitz, 09117, Germany
Elbe Kliniken Buxtehude
RECRUITING

Buxtehude, 21614, Germany
First Oc Dermatology Research Inc
RECRUITING

Fountain Valley, California, 92708-3701, United States
Fivenson Dermatology
RECRUITING

Ann Arbor, Michigan, 48103, United States
Fremantle Dermatology
RECRUITING

Fremantle, 06160, Australia
Grand Hopital de Charleroi - Site Imtr
RECRUITING

Gilly, 06060, Belgium
Guy'S Hospital - Guy'S & St Thomas' Nhs Foundation Trust
RECRUITING

London, SE1 9RT, United Kingdom
Hautarztpraxis Dr. Hoffmann
RECRUITING

Witten, 58453, Germany
Henry Ford Health System
RECRUITING

Detroit, Michigan, 48202, United States
High-Med. Przychodnia Specjalistyczna
RECRUITING

Warsaw, 01-817, Poland
Hospital Clinico Universitario San Cecilio
RECRUITING

Granada, 18016, Spain
Hospital General Universitario Dr Balmis
RECRUITING

Alicante, 03010, Spain
Hospital Universitari Germans Trias I Pujol (Hugtp)
RECRUITING

Badalona, 08916, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario La Paz
RECRUITING

Madrid, 28046, Spain
Hospital Universitario Puerta de Hierro de Majadahonda
COMPLETED

Majadahonda, 28222, Spain
Hospital Universitario Ramon Y Cajal
RECRUITING

Madrid, 28034, Spain
Hospital Universitario Reina Sofia
RECRUITING

Córdoba, 14004, Spain
Hospital Universitario Virgen Del Rocio
RECRUITING

Seville, 41013, Spain
Hospital de La Santa Creu I Sant Pau
COMPLETED

Barcelona, 08041, Spain
Hospital de Manises
RECRUITING

Manises, 46940, Spain
Investigate Md
COMPLETED

Scottsdale, Arizona, 85255, United States
Ipswich Hospital, East Suffolk and North Essex Nhs Foundation Trust
RECRUITING

Ipswich, IP4 5PD, United Kingdom
Klinikum Darmstadt
RECRUITING

Darmstadt, 64283, Germany
Klinikum Der Johann Wolfgang Goethe-Universitaet
RECRUITING

Frankfurt am Main, 60590, Germany
Klinikum Oldenburg Aor
RECRUITING

Oldenburg, 26133, Germany
Kume Derma Clinic
RECRUITING

Sakai, 593-8324, Japan
Luxderm Specjalistyczny Gabinet Dermatologiczny Prof. Dr. Hab. N. Med. Dorota Krasowska
RECRUITING

Lublin, 20-573, Poland
Magdeburger Company For Medical Studies and Services Gmbh
RECRUITING

Magdeburg, 39104, Germany
Medical Corporation Jun Dermatology Clinic
RECRUITING

Osaka, 558-0003, Japan
Medical Dermatology Specialists Phoenix
RECRUITING

Phoenix, Arizona, 85006, United States
Metro Boston Clinical Partners
COMPLETED

Brighton, Massachusetts, 02135-3511, United States
Michigan Dermatology Institute
RECRUITING

Waterford, Michigan, 48328, United States
Mics Centrum Medyczne Torun
RECRUITING

Torun, 87-100, Poland
Modern Research Associates Pllc
COMPLETED

Dallas, Texas, 75231, United States
National Defence Medical College Hospital
RECRUITING

Tokorozawa-shi, 359-8513, Japan
Niigata University Medical & Dental Hospital
RECRUITING

Niigata, 951-8520, Japan
Nippon Medical School Musashikosugi Hospital
RECRUITING

Kawasaki-shi, 211-8533, Japan
Nodal Medical Center, Llc
RECRUITING

Tampa, Florida, 33607, United States
Noguchi Dermatology Clinic
RECRUITING

Kamimashiki-gun, 861-3101, Japan
Nomura Dermatology Clinic
RECRUITING

Yokohama, 221-0825, Japan
North York Research Inc.
RECRUITING

Toronto, Ontario, M2N 3A6, Canada
Novatrials
RECRUITING

Charlestown, New South Wales, 02290, Australia
OPTISKIN
RECRUITING

New York, New York, 10128, United States
Paddington Testing Co Inc
RECRUITING

Philadelphia, Pennsylvania, 19103, United States
Panstwowy Instytut Medyczny Mswia
RECRUITING

Warsaw, 02-507, Poland
Poole Hospital - University Hospitals Dorset Nhs Foundation Trust
RECRUITING

Poole, BH15 2JB, United Kingdom
Premier Specialists Pty Ltd
RECRUITING

Kogarah, New South Wales, 02217, Australia
Queen'S Square Medical Facilities
RECRUITING

Yokohama, 220-6208, Japan
Rosenpark Research Gmbh
RECRUITING

Darmstadt, 64283, Germany
Royalderm Agnieszka Nawrocka
RECRUITING

Warsaw, 02-692, Poland
Sanatorium Profesora Arenbergera
RECRUITING

Prague, 110 00, Czechia
Sanixtra Prague
RECRUITING

Prague, 158 00, Czechia
Santa Familia Ptg Lodz
RECRUITING

Lodz, 90-302, Poland
Sapporo Skin Clinic
RECRUITING

Sapporo, 600063, Japan
Schweiger Dermatology
RECRUITING

Boca Raton, Florida, 33428, United States
Schweiger Dermatology
COMPLETED

Hackensack, New Jersey, 07601, United States
Shimizu Dermatology Clinic
RECRUITING

Kobe, 657-0846, Japan
Simcoderm Medical and Surgical Dermatology Centre
RECRUITING

Barrie, Ontario, L4M 7G1, Canada
Skin & Cancer Foundation Australia
RECRUITING

Sydney, New South Wales, 02010, Australia
Skin Care Research, Llc
RECRUITING

Hollywood, Florida, 33201, United States
Skin Physicians
RECRUITING

Edmonton, Alberta, T6W 4V4, Canada
Skinsense Medical Research
RECRUITING

Saskatoon, Saskatchewan, S7K 2C1, Canada
Surrey and Sussex Healthcare Nhs Trust - East Surrey Hospital
RECRUITING

Redhill, United Kingdom
Tanpopo Dermatology Clinic
RECRUITING

Ōta-ku, 143-0023, Japan
Technischen Universitaet Muenchen
RECRUITING

München, 80802, Germany
The Alfred Hospital
RECRUITING

Melbourne, Victoria, 03004, Australia
The Dudley Group Nhs Foundation Trust
RECRUITING

Dudley, DY1 2HQ, United Kingdom
The Royal London Hospital - Barts Health Nhs Trust
RECRUITING

London, E1 1FR, United Kingdom
Tohoku University Hospital
RECRUITING

Sendai, 980-8574, Japan
Tokyo Medical University Hospital
RECRUITING

Shinjuku-ku, 160-0023, Japan
Tokyo Medical University Ibaraki Medical Center - Kasumigaura Campus (Tokyo Medical University Kasum
RECRUITING

Inashiki-gun, Japan
Tokyo Medical and Dental University Hospital, Faculty of Medicine
RECRUITING

Bunkyō City, 113-8519, Japan
Toronto Research Centre
COMPLETED

Toronto, Ontario, M3H 5Y8, Canada
Trueblue Clinical Research Moore Clinical Research, Inc McR Tampa Clinic Location
COMPLETED

Tampa, Florida, 33609, United States
Universitaetsmedizin Goettingen
RECRUITING

Göttingen, 37075, Germany
Universitair Ziekenhuis Gent (Uz Gent)
RECRUITING

Ghent, 09000, Belgium
Universitat de Valencia - Hospital Universitari I Politecnic La Fe de Valencia (Hospital La Fe Bulev
RECRUITING

Valencia, 46026, Spain
Universite Catholique de Louvain (Ucl) - Cliniques Universitaires Saint-Luc
RECRUITING

Woluwe-Saint-Lambert, 01200, Belgium
University Hospital Carl Gustav Carus
RECRUITING

Dresden, 01307, Germany
University Hospital Muenster
RECRUITING

Münster, 48149, Germany
University Hospital Rwth Aachen
RECRUITING

Aachen, 52074, Germany
University of Cincinnati Cancer Institute
RECRUITING

Cincinnati, Ohio, 45267, United States
University of Maryland School of Medicine
RECRUITING

Baltimore, Maryland, 21201, United States
University of Occupational and Environmental Health, Japan
RECRUITING

Kitakyushu, 807-8555, Japan
University of Utah Midvalley Dermatology
COMPLETED

Murray, Utah, 84107, United States
Uniwersytecki Szpital Kliniczny Im. Fryderyka Chopina W Rzeszowie
RECRUITING

Rzeszów, 35-055, Poland
Veracity Clinical Research Pty Ltd
RECRUITING

Woolloongabba, Queensland, 04102, Australia
Westmead Hospital
RECRUITING

Westmead, New South Wales, 02145, Australia
Yardley Dermatology Associates
COMPLETED

Yardley, Pennsylvania, 19067, United States
Ziaderm Research, Llc
RECRUITING

Miami, Florida, 33162, United States

Conditions

Explore the condition pages connected to this study.

PRURIGO NODULARIS