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Can a simple antiseptic rinse improve sinus surgery recovery?

NCT ID NCT07470242

Disease control Sponsor: Pusan National University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether rinsing the nose with diluted povidone-iodine (a common antiseptic) after sinus surgery helps people with chronic sinusitis recover better than standard saline or mucomyst rinses. Forty-eight adults who had sinus surgery used one of the three rinses daily for three months. Researchers checked healing with a scope and tested hearing to see if the rinse caused any ear damage.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
povidone-iodine nasal irrigation
What this could lead to
If it works, this could offer a simple, low-cost option for improving sinus healing after surgery.
What could go wrong
This is a small, completed trial with only 48 participants, so results may not apply to everyone. There is also a risk of hearing damage (ototoxicity) with povidone-iodine.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

Oct 2021

Finished

Aug 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients diagnosed with chronic rhinosinusitis * Patients who underwent endoscopic sinus surgery (ESS) * Patients who performed postoperative nasal irrigation for 3 months * Patients who completed the follow-up evaluation and agreed to participate in the study Exclusion Criteria: * History of chronic otitis media * Presence of otitis media with effusion at the time of evaluation * History of previous middle ear surgery * Known allergy to povidone-iodine * Incomplete follow-up data * Refusal to participate in the study

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Conditions

The condition(s) this trial relates to.

chronic rhinosinusitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic rhinosinusitis

Contacts and locations

Locations

  • Pusan National University Hospital

    Pusan, 49241, South Korea

More trials for these conditions

Other studies related to the condition(s) this trial covers.