Memory boost for cocaine users? small study tests potassium channel blocker
NCT ID NCT07532460
First seen Apr 17, 2026 · Last updated Jun 23, 2026 · Updated 12 times
Summary
This study looks at whether a drug called fampridine, which blocks potassium channels in the brain, can improve working memory in people with cocaine use disorder. Forty chronic cocaine users will receive either the drug or a placebo and then take memory tests. The goal is to understand the brain mechanisms behind cognitive problems in cocaine users, not to test a cure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Hospital of Psychiatry Zurich
Zurich, Canton of Zurich, 8008, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fampridine (4-aminopyridine)
What this could lead to
If it works, this could point toward a treatment for cognitive impairments in people with cocaine use disorder.
What could go wrong
This is a very small, early-stage study with only 40 participants. It tests a single dose, so any effects may be temporary or not translate to real-world benefits.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.