Can blood pressure meds after delivery keep new moms out of the hospital?
NCT ID NCT04298034
First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times
Summary
This study tests whether giving blood pressure medication to women after childbirth can prevent hospital readmissions and reduce severe high blood pressure. About 300 women with preeclampsia will either receive standard care or start blood pressure drugs like labetalol or nifedipine. The goal is to see if treatment lowers the need for extra medical visits and improves recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Labetalol and Nifedipine (blood pressure medications)
- What this could lead to
- If successful, this could show that treating high blood pressure after childbirth reduces hospital readmissions and the need for extra doctor visits for women with preeclampsia.
- What could go wrong
- This is a Phase 3 trial, but it only compares treatment to no treatment, not to a placebo. Results may not apply to all women, and the medications can have side effects like dizziness or fatigue.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2020
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \>= 18 years old * Immediately postpartum (delivered in previous 96 hours) * Diagnosed with preeclampsia during pregnancy, labor or immediately postpartum * \>30% of blood pressures in the postpartum period were elevated (systolic 140 or higher OR diastolic 90 or higher) Exclusion Criteria: * Chronic hypertension with superimposed preeclampsia * Diagnosis of preeclampsia after discharge from delivery hospitalization * Persistent severe range blood pressures after delivery requiring initiation of antihypertensive regimen by the care team * \>50% of blood pressures in the postpartum period were normal (systolic less than 140 AND diastolic less than 90)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Medical College of Wisconsin-Froedtert Hospital
Milwaukee, Wisconsin, 53226, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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