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New study aims to protect Kids' kidneys after surgery

NCT ID NCT07351149

Knowledge-focused Sponsor: Uppsala University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study observes 2000 children aged 0-16 who have noncardiac surgery to see how often kidney injury occurs. Researchers will also test urine markers for early detection. The goal is to find risk factors and improve prevention strategies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could lead to better ways to prevent and detect kidney injury after surgery in children.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly benefit participants. Results may not apply to all hospitals or children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 2,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Hospitalised paediatric patients undergoing major non-cardiac surgery in any of the specified investigator sites

Ages

0 to 16 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Elective, urgent or emergency in-patient major non-cardiac surgical procedures performed under general anaesthesia with or without regional analgesia with a planned procedure duration of at least 60 minutes. * Paediatric patients (0-16 years old) Exclusion Criteria: * Declined participation. * Ongoing renal replacement therapy * Acute Kidney Injury (according to KDIGO) * Known chronic kidney disease * Procedure involving surgery of the kidney * Procedures requiring clamping of blood flow to or from the kidney * Body weight \<2kg * Procedure involving contrast administration * Established rhabdomyolysis (CK-levels \>1500 U/L)

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    13 sites in 7 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospices Civils de Lyon

    NOT_YET_RECRUITING

    Lyon, France

  • Hospital das Clínicas HCFMUSP

    NOT_YET_RECRUITING

    São Paulo, Brazil

  • IRCCS Istituto Giannina Gaslini

    NOT_YET_RECRUITING

    Genova, Italy

  • Karolinska University Hospital

    RECRUITING

    Stockholm, Sweden

  • Perth Children's Hospital

    NOT_YET_RECRUITING

    Perth, Western Australia, 6909, Australia

  • Sahlgrenska University Hospital

    NOT_YET_RECRUITING

    Gothenburg, Sweden

  • Skåne University Hospital

    NOT_YET_RECRUITING

    Lund, Sweden

  • The Kids Research Institute Australia

    NOT_YET_RECRUITING

    Perth, Western Australia, 6909, Australia

  • University Hospital Basel

    NOT_YET_RECRUITING

    Basel, Switzerland

  • University Hospital Bern

    NOT_YET_RECRUITING

    Bern, Switzerland

  • University Hospital Geneva

    NOT_YET_RECRUITING

    Geneva, Switzerland

  • University Hospital of Belgrade

    NOT_YET_RECRUITING

    Belgrade, Serbia

  • Uppsala University Hospital

    RECRUITING

    Uppsala, Sweden

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