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Radiation after spine surgery: does it help?

NCT ID NCT07527884

Disease control Sponsor: Wei Xu Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 17, 2026 · Updated 3 times

Summary

This study will follow 130 people who had surgery for cancer that spread to the spine. Half will get radiation after surgery, half will not. Researchers want to see if radiation helps keep the cancer from coming back and improves how long patients live. The goal is to help doctors make better treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
radiotherapy
What this could lead to
If this trial succeeds, it could show that adding radiotherapy after surgery helps control spinal tumors longer and improves survival.
What could go wrong
This is an observational study, not a randomized trial, so results may be less definitive. It is also early-stage with only 130 participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 130 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Sep 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age over 18 years old, gender not limited; 2. The patient has undergone separation surgery within 3 weeks; 3. The pathological result of the separation surgery site of the patient indicates that the lesion is a metastatic tumor, and the primary lesion is located outside the spine; 4. The expected survival period is ≥ 6 months; 5. The patient has signed the informed consent form. Exclusion Criteria: 1. Patients with poor general condition and those who are intolerant to radiotherapy, chemotherapy, and targeted therapy; 2. Patients whose treatment segments have not received any other surgical treatment or radiotherapy; 3. Patients who participated in other clinical trials of drugs or medical devices within 3 months before enrollment; 4. Other situations judged by the investigator as making the subject unsuitable for enrollment.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm in the spinal cord spinal cord cancer spinal cord neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Radiotherapy Separation surgery Spinal metastases Spinal tumor

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Shanghai Changzheng Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200003, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.