Could a postbiotic ease severe IBS diarrhea? new trial results in
NCT ID NCT06346847
First seen Mar 25, 2026 · Last updated Jun 16, 2026 · Updated 11 times
Summary
This study tested whether a postbiotic supplement can reduce belly pain and other symptoms in people with moderate to severe diarrhea-predominant irritable bowel syndrome (IBS-D). 384 adults aged 18 to 55 took either the postbiotic or a placebo for 12 weeks, then stopped for 3 weeks. The main goal was to see if more people felt at least a 50-point improvement on a symptom severity scale. The trial also checked effects on anxiety, mood, and stress.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Anand Multispeciality Hospital
Vadodara, Gujarat, 390016, India
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Apollo Hospital
Navi Mumbai, Maharashtra, 400614, India
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Asian Institute of Medical sciences
Thane, Maharashtra, 421203, India
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Astha Clinic
Nashik, Maharashtra, 422011, India
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Astha Clinic
Nashik, India
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Birch Multispeciality Hospital
Maharashtra, 411041, India
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Criticare Asia Multispeciality Hospital & Research Centre
Mumbai, Maharashtra, 400069, India
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Ford Hospital
Uttar Pradesh, 221005, India
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GCS Medical College, Hospital & Research Centre
Gujarat, 380025, India
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Gastrohub Hospital
Pune, Maharashtra, 411027, India
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HCG Hospital
Ahmedabad, Gujarat, 380006, India
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Human care hospital
Uttar Pradesh, 226012, India
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Lifeline Multispeciality Hospital
Pune, Maharashtra, 412101, India
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Lifeline multispeciality hospital
Maharashtra, 412101, India
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Maharaja Agrasen Superspeciality Hospital
Jaipur, Rajasthan, 302039, India
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Maharaja Agrasen Superspeciality Hospital
Jaipur, India
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Mata Roop Rani Maggo Hospital & IVF Center
New Delhi, 110059, India
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Nand Hospital
Gujarat, 390015, India
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Samvedna Hospital
Varanasi, Uttar Pradesh, 221005, India
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Stress Test Clinic
Mumbai, Maharashtra, 400059, India
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Surya Multispeciality Hospital
Nashik, Maharashtra, 422003, India
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Swara Hospital
Pālghar, Maharashtra, 401303, India
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Umarji Mother and Child Care Hospital
Pune, Maharashtra, 411045, India
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.