Eczema breakthrough? postbiotic cream may keep Kids' skin calm

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Participants must meet the diagnostic criteria established by Williams. 2. Moderate atopic dermatitis is defined by an Eczema Area and Severity Index (EASI) score of 7.1 to 21.0, and an Investigator's Global Assessment (IGA) score of 3. 3. Age range is 0 to 6 years, with no gender restrictions. 4. Guardians of the participants must be willing to apply the test product to the participants as directed by the physician throughout the study period. 5. Participants should not have received topical medication within 14 days prior to enrollment, including calcineurin inhibitors (e.g., topical tacrolimus or pimecrolimus), corticosteroid formulations, or topical antihistamines. 6. Within 4 weeks prior to enrollment, participants should not have received non-steroidal immunosuppressants (e.g., cyclosporine, methotrexate) or phototherapy, nor should they have used systemic corticosteroids or systemic antihistamines. 7. Participants are not allowed to use other similar products during the entire study period. 8. Prior to the commencement of any study-specific examination or procedural step, participants must sign an informed consent form. For infants and young children aged 0 to 6 years, the guardians must sign an informed consent waiver on behalf of the child and also sign a parental version of the informed consent form. Exclusion Criteria: 1. Do not meet the diagnostic criteria established by Williams. 2. Children with acute exacerbation characterized by erosion, exudation, or secondary infection. 3. Presence of open skin infections (bacterial, viral, or fungal) at the application site. 4. Children currently participating in other clinical studies or having participated within the last 3 months. 5. Children who have received topical medication within 14 days prior to enrollment, including calcineurin inhibitors (e.g., topical tacrolimus or pimecrolimus), corticosteroid formulations, or topical antihistamines. 6. Children who have received non-steroidal immunosuppressants (e.g., cyclosporine, methotrexate) or phototherapy, systemic corticosteroids, or systemic antihistamines within 4 weeks prior to enrollment. 7. Children with severe immune system disorders (such as lymphoma, AIDS, Wiskott-Aldrich syndrome) or a history of malignant tumors. 8. Children with severe heart, liver, or kidney diseases. 9. Children with other skin diseases in the treatment area besides atopic dermatitis. 10. Known allergy to hydrocortisone butyrate cream or the test product. 11. Poor compliance of the subject, known inability to attend visits on time, or unwillingness to comply with the study protocol during the study period. 12. Any condition or previous/concurrent treatment that makes the subject ineligible for this study.