Can a migraine drug stop headaches after a concussion?

NCT ID NCT04098250

Completed Disease control Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This study looked at whether the migraine drug erenumab can help people with headaches that start after a mild traumatic brain injury (concussion). Six adults with recent post-traumatic headaches were given either the drug or a placebo. The goal was to see if the drug reduced the number of moderate-to-severe headache days and to learn more about what causes these headaches to persist.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Mayo Clinic

Phoenix, Arizona, 85054, United States
Mayo Clinic

Jacksonville, Florida, 32224, United States
Mayo Clinic

Rochester, Minnesota, 55901, United States
Mayo Clinic in Arizona

Scottsdale, Arizona, 85259, United States
Phoenix VA Health Care System

Phoenix, Arizona, 85012, United States

Conditions

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POST-TRAUMATIC HEADACHE POST-TRAUMATIC HEADACHE