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Can vitamin e and a blood flow drug ease radiation scarring?

NCT ID NCT03723291

First seen Mar 10, 2026 · Last updated May 21, 2026 · Updated 8 times

Summary

This study tested whether taking pentoxifylline (a blood flow drug) and vitamin E together can help reduce scarring and tightness in the throat and jaw caused by radiation therapy for head and neck cancer. 50 adults who had radiation at least a year ago and were cancer-free took the drugs plus did rehabilitation exercises for 6 months. The main goal was to see if a larger trial is possible, not to prove the treatment works.

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Contacts and locations

Locations

  • Aintree University Hospital NHS Foundation Trust

    Liverpool, United Kingdom

  • University College London Hospitals NHS Foundation Trust

    London, United Kingdom

Conditions

Explore the condition pages connected to this study.