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Less frequent port flushing may be safe for cancer patients

NCT ID NCT05454189

Disease control Sponsor: Essentia Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether it is safe to flush implanted port devices every 12 weeks instead of the standard every 4 weeks. Ports are small devices placed under the skin to give chemotherapy safely. The study involves 400 cancer patients and will compare how well the ports work and how often complications occur between the two schedules. If successful, it could mean fewer trips to the clinic for patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
implanted port device flushing schedule
What this could lead to
If successful, this could allow cancer patients to have their port flushed less often, reducing clinic visits and inconvenience.
What could go wrong
This is a relatively small, single-center study. Less frequent flushing might increase the risk of blockages or infections, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 400 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2022

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Hematology/Oncology patients ≥ 18 years old with an Implanted Port Device. * No planned clinical visits for at least 12 weeks. * No planned need to access Implanted Port Device within next 12 weeks outside of routine flushing. Potential reasons to access can include but are not limited to lab draw, infusion, IV contrast. * No planned removal of IPD within 12 weeks of registration. * No Deep Vein Thrombosis or significant Implanted Port Device complication within ≤ 4 weeks of registration. * Patient Implanted Port Device with documented blood return ≤ 14 days of registration. * Ability to read and speak English. * Able to give informed consent. Exclusion Criteria: * Allergy to heparin * Vulnerable populations: pregnant women, prisoners, mentally handicapped.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Maintenance of implanted port devices

Contacts and locations

Locations

  • Essentia Health Deer River Clinic

    Deer River, Minnesota, 56636, United States

  • Essentia Health Duluth Clinic

    Duluth, Minnesota, 55805, United States

  • Essentia Health Fargo

    Fargo, North Dakota, 58103, United States

  • Essentia Health Fosston

    Fosston, Minnesota, 56542, United States

  • Essentia Health Hibbing Clinic

    Hibbing, Minnesota, 55746, United States

  • Essentia Health Park Rapids

    Park Rapids, Minnesota, 56470, United States

  • Essentia Health Sandstone

    Sandstone, Minnesota, 55072, United States

  • Essentia Health St Mary's Detroit Lakes Clinic

    Detroit Lakes, Minnesota, 56501, United States

  • Essentia Health St. Joseph's Medical Center

    Brainerd, Minnesota, 56401, United States

  • Essentia Health Virginia Clinic

    Virginia, Minnesota, 55792, United States

  • Fairview Grand Itasca Clinic & Hospital

    Grand Rapids, Minnesota, 55744, United States

  • Fairview Northland Medical Center

    Princeton, Minnesota, 55371, United States

  • Fairview Range Medical Center

    Hibbing, Minnesota, 55746, United States

  • Mayo Clinic Health System - Albert Lea

    Albert Lea, Minnesota, 56007, United States

  • Mayo Clinic Health System - Mankato

    Mankato, Minnesota, 56001, United States

  • Monticello Cancer center

    Monticello, Minnesota, 55362, United States

  • Sanford Worthington Medical Center

    Worthington, Minnesota, 56187, United States