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10,000 french volunteers give DNA to help doctors spot disease genes

NCT ID NCT04183023

First seen Apr 01, 2026 · Last updated Jun 23, 2026 · Updated 11 times

Summary

This study collects saliva samples from 10,000 healthy French volunteers to create a reference database of common genetic variations. By knowing what's normal in the general population, doctors can more easily identify rare, disease-causing mutations in patients. The project is part of France's plan to bring genome sequencing into routine medical care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Inserm - UMR1078 GGB

    Brest, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this will create a detailed map of normal genetic variation in the French population, making it easier to spot disease-causing mutations and speed up rare disease diagnoses.

What could go wrong

This is an observational study, not a treatment trial. It builds a reference database, so there is no direct benefit to participants. The results may not apply to people outside France or those with mixed ancestry.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.