New combo targets tough leukemia in adults
NCT ID NCT05306301
First seen Mar 16, 2026 · Last updated May 23, 2026 · Updated 7 times
Summary
This study tests a drug called ponatinib combined with chemotherapy as a first treatment for adults aged 18-65 with a high-risk type of acute lymphoblastic leukemia (BCR/ABL1-like ALL). The goal is to see if this targeted approach can make the cancer undetectable in the bone marrow after three cycles. About 32 participants will receive the treatment to measure how well it works.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dipartimento di Medicina Traslazionale e di Precisione - Ematologia
Roma, Italy
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Ematologi Presidio Ospedaliero Guglielmo da Saliceto
Piacenza, Italy
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Ematologia AO Ospedali Riuniti Villa Sofia Cervello
Palermo, Italy
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Ematologia AOU Careggi
Florence, Italy
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Ematologia AOU Federico II
Naples, Italy
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Ematologia AOU Maggiore della Carità
Novara, Italy
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Ematologia AOU Policlinico Tor Vergata
Roma, Italy
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Ematologia AOU Policlinico Vittorio Emanuele-Ferrarotto
Catania, Italy
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Ematologia AOU S.ORSOLA-MALPIGHI
Bologna, Italy
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Ematologia AOU Senese
Siena, Italy
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Ematologia ASST Papa Giovanni XXIII
Bergamo, Italy
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Ematologia ASST Spedali Civili
Brescia, Italy
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Ematologia Fondazione Policlinico San Matteo
Pavia, Italy
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Ematologia Ospedale Maggiore Policlinico
Milan, Italy
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Ematologia Ospedale Mauriziano
Torino, Italy
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Ematologia Ospedale S.Giovanni Battista Molinette
Torino, Italy
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Ematologia Ospedale V.Fazzi
Lecce, Italy
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Ematologia Ospedale dell'Angelo
Mestre, Italy
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Ematologia Policlinico A.Gemelli
Roma, Italy
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Ematologia Policlinico G.B. Rossi
Verona, Italy
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Ematologia Presidio Ospedaliero Infermi
Rimini, Italy
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Ematologia Presidio Ospedaliero Spirito Santo
Pescara, Italy
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Ematologia Presidio Ospedaliero Tortora
Pagani, SA, Italy
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Ematologia con Unità di Trapianto
Avellino, AV, 83100, Italy
Conditions
Explore the condition pages connected to this study.