Pollution alerts tested as asthma aid for children
NCT ID NCT07261423
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving children with asthma and their families Air Quality Index (AQI) information helps improve asthma control. 351 children will receive either EPA or commercial AQI education plus an asthma action plan, or standard care. Over 48 weeks, researchers will track asthma control scores, quality of life, and nasal gene changes to see if pollution awareness makes a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Air Quality Index (AQI) education and usage instructions
- What this could lead to
- If it works, this could give families a simple tool to reduce asthma flare-ups triggered by outdoor air pollution.
- What could go wrong
- This is a behavioral study, not a drug trial. The effect may be small, and results depend on families consistently using the AQI information.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 351 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Jan 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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8 to 17 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * A healthcare provider diagnosis of persistent asthma (Steps 2-5 as defined by US guidelines) or intermittent asthma (Step 1) + at least one severe asthma exacerbation (defined by American Thoracic Society (ATS)/European Respiratory Society (ERS) criteria as requiring at least 3 days of systemic steroids or an Emergency Department/Urgent Care visit requiring systemic steroids) in the prior 12 months * Home access to a smartphone or internet * Primary residence in Allegheny County, PA * One participant per household * Age 8 -17 years * Healthcare provider evaluation for asthma in the prior year Exclusion Criteria: * Diagnosis of other active chronic respiratory diseases (e.g., cystic fibrosis, bronchopulmonary dysplasia, etc.) * Neuromuscular disorder * Chronic disorder limiting independent ambulation (e.g., spastic quadriplegia, etc.) * Cyanotic heart disease * Plans to relocate from Allegheny County, PA in the next year (12 months) * Use of intranasal or oral/intramuscular/intravenous corticosteroids 4 weeks prior to randomization * Current participation in another asthma intervention trial
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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UPMC Children's Hospital of Pittsburgh
RECRUITINGPittsburgh, Pennsylvania, 15224, United States
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