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Easy and hard exercise combo may boost heart health in couch potatoes

NCT ID NCT07665632

Knowledge-focused Sponsor: University of Ljubljana Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 25, 2026 · Updated 2 times

Summary

This study tests whether a 6-week polarized aerobic training program—mixing easy and hard cycling sessions—can improve blood vessel and heart function in sedentary adults aged 30-50. Thirty participants will either exercise three times a week or continue their usual habits. Researchers will measure changes in artery health, fitness, and blood markers to see if this training approach works for non-athletes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Polarized aerobic training (cycle ergometer exercise)
What this could lead to
If successful, this could show that a specific mix of easy and hard exercise improves blood vessel health and fitness in sedentary adults, pointing toward better exercise programs for heart health.
What could go wrong
This is a small, early-stage study with only 30 participants. Results may not apply to everyone, and the exercise program may not produce meaningful changes in blood vessel function.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men and women aged 30-50 years * Apparently healthy individuals without diagnosed cardiovascular, metabolic, or renal disease * Sedentary lifestyle verified using the Global Physical Activity Questionnaire (GPAQ) and current physical activity classification criteria * Ambulatory blood pressure values within the normotensive range (\<140 mmHg systolic and \<90 mmHg diastolic) * Body mass index (BMI) \<30 kg/m² * No regular participation in structured exercise training Exclusion Criteria: * Ambulatory blood pressure values ≥140 mmHg systolic and/or ≥90 mmHg diastolic * Moderate or high physical activity level according to the Global Physical Activity Questionnaire (GPAQ) * Diagnosed chronic cardiovascular, metabolic, renal, respiratory, or other systemic disease * Use of prescribed medication influencing cardiovascular or metabolic function * Musculoskeletal injury of the lower extremities within the previous six months * Menopause * Absence of a regular menstrual cycle * Pregnancy * Current smoking or tobacco use

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Conditions

The condition(s) this trial relates to.

Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sedentary lifestyle

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Ljubljana, Faculty of sport

    RECRUITING

    Ljubljana, 1000, Slovenia

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