New knee implant tracked for 5 years in 777 patients
NCT ID NCT02337244
First seen Jan 06, 2026
Summary
This study follows 777 adults aged 18-75 who received the Persona Total Knee System to treat severe knee pain and disability from conditions like osteoarthritis or rheumatoid arthritis. Researchers will track how long the implant lasts, how safe it is, and how well it improves pain and function over 5 years. The goal is to gather real-world data on the implant's performance.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
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Locations
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Atos Klinik Heidelberg
Heidelberg, Germany
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CHU de Clermont-Ferrand
Clermont-Ferrand, 63003, France
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Centre Hospitalier régional Universitaire de Montpellier
Montpellier, 34980, France
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Golden Jubilee National Hospital
Clydebank, United Kingdom
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HEH Braunschweig
Braunschweig, Germany
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Harrogate and District NHS
Harrogate, HG2 7SX, United Kingdom
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Hospital Miguel Servet
Zaragoza, Spain
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Hospital Parc Tauli
Sabadell, Spain
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Orthopädisches Spital Speising
Vienna, 1130, Austria
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Stichting Research Orthopedie & Reinier de Graaf Groep
Delft, 2612, Netherlands
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The Newcastle Upon Tyne Hospitals
Newcastle, United Kingdom
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University of Leeds
Leeds, Leeds/UK, LS2 9JT, United Kingdom
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Zimmer Persona Total Knee System (artificial knee implant)
What this could lead to
If successful, this could confirm that the Persona knee implant provides long-lasting pain relief and improved function for people with severe knee arthritis.
What could go wrong
This is an observational study, not a controlled trial, so results may not prove the implant is better than other options. Some patients may still experience complications like implant loosening or infection.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.