Can better nutrition help kids beat cancer?
NCT ID NCT06175273
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
Nearly 60% of children with cancer become malnourished, which can lead to infections and worse outcomes. This pilot study tested three nutrition approaches—oral supplements, appetite-stimulating drugs, and tube feeding—in 19 children to see which best improved body composition and weight. The goal is to create clear guidelines for doctors to use in the future.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Oral nutrition supplement, tube feeding, cyproheptadine, olanzapine
- What this could lead to
- If successful, this could lead to better clinical guidelines for managing malnutrition in children with cancer, potentially improving treatment outcomes and survival.
- What could go wrong
- This is a small pilot study with only 19 participants, so results may not apply to all children. The interventions have side effects, and the study does not test whether they improve cancer outcomes directly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2/3
Runs two stages together: whether the treatment works, then large-scale confirmation.
- Participants
-
19 people
The number who actually took part.
- Started
-
Jan 2024
- Finished
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Aug 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
2 to 19 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * New diagnosis of pediatric cancer Exclusion Criteria: * Current use or history of enteral nutrition, oral supplement, or orexigenic/anorectic use.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Kentucky
Lexington, Kentucky, 40536, United States
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