Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

New study aims to uncover why COVID-19 harms organs months later

NCT ID NCT06608849

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 345 adults to learn how COVID-19 may cause lasting damage to the lungs, heart, and kidneys. Researchers will compare people who had COVID-19 with those who did not, using blood tests, breathing tests, and heart scans. The goal is to find early warning signs and create guidelines to prevent long-term health problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better tools for predicting and preventing long-term organ damage after COVID-19.
What could go wrong
This is an observational study, not a treatment trial. It will not test any new drug or therapy, so it cannot directly improve health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 345 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2024

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

POINT will include patients who have participated in the studies ESCAPE, SAVE, SAVE-MORE and SAVE-LONG. For these patients blood samples and clinical data are already available (Baseline - Year 0 from ESCAPE, SAVE \& SAVE-MORE and Year 1 from SAVE-LONG). POINT needs to enroll three groups of patients (selected by the existing biobank mentioned above, based on the inclusion and exclusion study criteria) to cover the magnitude of the spectrum of COVID-19: * Group A (115 Comparators): Comparators without medical history of acute infection by SARS-CoV-2. * Group B (115 with NO dysfunction): Patients fully recovered by acute COVID-19 who did not present any acute organ injury during acute infection by SARS-CoV-2. * Group C (115 with Dysfunctions): Patients who presented signs of lung, heart, and kidney dysfunction during acute infection by SARS-CoV-2.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Group A (comparators) 1. Adults (18 years or more) of both genders 2. Negative history of acute COVID-19 Group B (patients with ΝΟ dysfunction) 1. Adults (18 years or more) of both genders 2. History of acute COVID-19 hospitalized or non-hospitalized. All cases appearing from start of the pandemic until the last six months may apply 3. Absence of any current overt organ dysfunction 4. Absence of signs of any organ dysfunction during acute COVID-19 Group C (patients with dysfunctions) 1. Adults (18 years or more) of both genders 2. History of acute COVID-19 hospitalized or non-hospitalized. All cases appearing from start of the pandemic until the last six months may apply 3. Presence of signs of organ dysfunction of the lung, the kidneys or the heart during acute COVID-19 Exclusion Criteria: Group A (comparators) 1. Any other co-existing disorder generating clinical symptoms 2. Failure to thrive according to the attending physicians 3. Pregnancy or lactation Group B (patients with ΝΟ dysfunction) 1. Any other co-existing disorder generating clinical symptoms 2. Failure to thrive according to the attending physicians 3. Pregnancy or lactation Group C (patients with dysfunctions) 1. Any other co-existing disorder generating clinical symptoms 2. Medical history of any of: * stage III or IV chronic obstructive pulmonary disease according to the GOLD criteria * pulmonary fibrosis or pulmonary hypertension * stage IV solid tumour malignancy under chemotherapy or radiotherapy * systemic sclerosis * congestive heart failure * stage II, III or IV dyspnoea according to the New York Heart Association classification before the acute COVID-19 3. Limited chance of survival for at least six months due to co-existing comorbidity(-ies) according to the judgement of the attending physicians 4. Pregnancy or lactation

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Cardiovascular complications are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    6 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • 10th Department of Pulmonary Medicine, Sotiria Athens Hospital of Chest Diseases

    RECRUITING

    Athens, Greece

  • 1st Department of Internal Medicine, Thriasio General Hospital of Elefsina

    RECRUITING

    Elefsina, Greece

  • 2nd Department of Internal Medicine, Thriasio General Hospital of Elefsina

    RECRUITING

    Elefsina, Greece

  • 4th Department of Internal Medicine, ATTIKON University General Hospital

    RECRUITING

    Athens, Greece

  • Obstructive Diseases Clinic, Sotiria Athens Hospital of Chest Diseases

    RECRUITING

    Athens, Greece

  • Out-patient department of Infectious Diseases, Sotiria Athens Hospital of Chest Diseases

    RECRUITING

    Athens, Greece

More trials for these conditions

Other studies related to the condition(s) this trial covers.