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Could targeted exercises rebuild strength after Guillain-Barré?

NCT ID NCT07745556

Symptom relief Sponsor: Rida Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 04, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This trial tests whether combining proprioceptive neuromuscular facilitation (a type of stretching that improves flexibility and strength) with core strengthening exercises can help people with Guillain-Barré syndrome recover balance, muscle strength, and the ability to perform daily activities. About 32 adults in the subacute or recovery stage (2 to 12 weeks after onset) will be randomly assigned to either this exercise program or conventional physical therapy. The exercises are done four times a week for eight weeks, with progress measured using standard balance, strength, and daily-living scales.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Proprioceptive neuromuscular facilitation (PNF) combined with core strengthening exercises
What this could lead to
If effective, this combination of stretching and core exercises could offer a way to improve balance, strength, and daily living skills for people recovering from Guillain-Barré syndrome.
What could go wrong
This is a small early-stage trial, so results may not apply to everyone. The exercises are generally safe but could cause muscle soreness or fatigue.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

Feb 2026

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * participants diagnosed with Guillain Barré Syndrome (GBS) based on neurological criteria * At the subacute or recovery stage of GBS, meaning within two to 12 weeks from disease onset * Age ranges from 18 to 45 years * Gender does not matter; both males and females can participate * Medical stability of the patient and being medically cleared to engage in intensive rehabilitation by a physical Ability to give informed consent Exclusion Criteria: * Patients with cognitive disabilities and those who cannot follow commands * Patients with unstable heart and breathing rates and other systemic disease * Patients refusing to give their informed consent * Presence of musculoskeletal problems with balance problems (recent fractures, arthritis)

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Conditions

The condition(s) this trial relates to.

Guillain-Barre syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Guillain Barré syndrome

Contacts and locations

Locations

  • University of Lahore teaching hospital, Lahore

    Lahore, Punjab Province, 54000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.