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Short therapy shows promise for depression and anxiety in primary care

NCT ID NCT06988332

Symptom relief Sponsor: University of Chile Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a short psychological program called Problem Management Plus (PM+) for adults with depression or anxiety in a primary care clinic in Chile. The program involves five 90-minute sessions teaching problem-solving and stress management skills, delivered by healthcare workers without mental health expertise. The trial compared PM+ to usual care in 56 participants, focusing on whether the program was feasible and acceptable, and whether it helped reduce symptoms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Problem Management Plus (PM+)
What this could lead to
If it works, this could provide a simple, low-cost psychological treatment for depression and anxiety that can be delivered by non-specialists in primary care settings.
What could go wrong
This is a very small pilot study with only 56 participants, focused on feasibility and preliminary effects. The results may not be generalizable, and larger trials are needed to confirm any benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Started

May 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals over 18 years old. * Diagnosed with or presenting depressive and/or anxiety symptoms (through screening). * Residents of the selected study region. * Part of the population enrolled and validated in the pilot primary health care facilities. Exclusion Criteria: * Suicidal risk requiring immediate or urgent referral to care services. * Suffering from severe psychiatric disorders or substance use disorders. * Being in situations of declared risk that require protection (e.g., domestic violence). * Moderate or severe disability. * Incapacitating medical illnesses. * Receiving other mental health treatments that could lead to over-intervention.

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Conditions

The condition(s) this trial relates to.

anxiety disorder depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety disorders Depressive disorder

Contacts and locations

Locations

  • CESFAM Las Ánimas

    Valdivia, Chile

More trials for these conditions

Other studies related to the condition(s) this trial covers.