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Scientists collect chest tumor samples to unlock secrets of cancer spread

NCT ID NCT04844827

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study collected tissue and blood samples from 143 people with malignant pleural effusion (cancer that has spread to the lining of the chest). The goal was to create a biobank for future research into why cancer cells in the chest may differ from the original tumor. No treatment was given; the focus was on gathering samples for later analysis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this biobank could help researchers understand why cancer cells in the chest lining differ from the original tumor, potentially pointing toward better treatments.
What could go wrong
This is a tissue-collection study, not a treatment trial. It does not test any therapy, and any future benefits depend on many years of additional research.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

143 people

The number who actually took part.

Started

Nov 2022

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study concerns adult patients with pleural metastasis eligible for a surgical exploration of the pleura

Ages

18 to 110 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female over 18 years old * Malignant pleural effusion with or without prior histological or cytological diagnosis * Patient eligible for a pleural biopsy for diagnostic purposes and validated in a multidisciplinary consultation meeting * Having given their free and informed writing consent * Affiliated to a social security system or assimilated Exclusion Criteria: * Malignant pleural mesothelioma * Contraindication to general anesthesia * Pregnant or breastfeeding woman, or is of child bearing potential and who did not agree to use highly effective methods of birth control throughout the study. * Patient participating in a interventional study likely to interfere with this study * Patient benefiting from a legal protection measure (guardianship or curatorship)

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Conditions

The condition(s) this trial relates to.

pleural cancer Pleural Effusion, Malignant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pleural effusion, malignant

Contacts and locations

Locations

  • Louis Pradel Hospital

    Bron, 69500, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.