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New pill takes on hard-to-treat lung cancer in major trial

NCT ID NCT06281964

First seen Dec 29, 2025 · Last updated Jun 16, 2026 · Updated 28 times

Summary

This study tests a new drug called PLB1004 against standard chemotherapy for people with advanced non-small-cell lung cancer that has a specific genetic change (EGFR exon 20 insertion). About 327 adults with this cancer type will be randomly assigned to receive either PLB1004 or chemotherapy. The main goal is to see if PLB1004 can delay cancer growth better than standard treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Guangdong Provincial People's Hospital

    Guangzhou, Guangzhou, 510080, China

Conditions

The condition(s) this trial relates to.

lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.