Blood-Based injection shows promise for slowing dry AMD
NCT ID NCT07428798
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether injecting a concentrated form of a patient's own blood, called platelet-rich plasma (PRP), into the eye could slow the progression of advanced dry age-related macular degeneration (AMD). Fourteen people with advanced dry AMD received three PRP injections in one eye, while the other eye was left untreated as a comparison. The goal was to see if the treatment could reduce the growth of damaged areas in the retina and help preserve vision.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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14 people
The number who actually took part.
- Started
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Jul 2024
- Finished
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Oct 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age ≥ 60 years 2. Diagnosis of advanced dry age-related macular degeneration (AMD) in both eyes 3. No previous ocular treatment for AMD 4. History of ocular surgery limited to cataract surgery performed ≥1 year prior Exclusion Criteria: 1. Media opacities interfering with retinal imaging assessment 2. Any ocular disease other than dry AMD that could affect retinal structure or function 3. Evidence of macular neovascularization 4. Previous intraocular surgery other than cataract surgery 5. Systemic or ocular conditions that could affect study compliance or visual testing reliability
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Marmara University School of Medicine, Department of Ophthalmology
Istanbul, Istanbul, 34899, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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