New booster shot for Cancer-Fighting cells may keep leukemia away longer

This study tests a new approach to help children and young adults with a type of leukemia (CD19+ acute leukemia) that has come back or not responded to treatment. After patients receive CAR T cell therapy, their cancer-fighting cells can fade over time, allowing the leukemia to return. Researchers will give patients periodic infusions of special "booster" cells (T-APCs) designed to keep the CAR T cells active longer. The goal is to see if this is safe and can reduce the chance of relapse. About 30 participants will be enrolled.