New booster shot for Cancer-Fighting cells may keep leukemia away longer

NCT ID NCT03186118

First seen Jun 07, 2026 · Last updated Jun 11, 2026 · Updated 1 time

Summary

This study tests a new approach to help children and young adults with a type of leukemia (CD19+ acute leukemia) that has come back or not responded to treatment. After patients receive CAR T cell therapy, their cancer-fighting cells can fade over time, allowing the leukemia to return. Researchers will give patients periodic infusions of special "booster" cells (T-APCs) designed to keep the CAR T cells active longer. The goal is to see if this is safe and can reduce the chance of relapse. About 30 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

Conditions

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Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.