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Could a plant-based supplement calm chemo-related diarrhea?

NCT ID NCT07460596

Symptom relief Sponsor: Tianjin Medical University Cancer Institute and Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial tested a concentrated plant dietary supplement (made from foods like taro, rice, and carrots) in 30 people with gastrointestinal cancers who had diarrhea from chemotherapy. Participants received the supplement alongside standard anti-diarrheal treatment. The goal was to see if it could help stop diarrhea faster. The study was small and had no placebo group, so results are preliminary.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Concentrated Phytodietary Compound (a dietary supplement made from plant foods like taro, rice, and carrots)
What this could lead to
If it works, this could offer a natural, food-based option to help manage chemotherapy-induced diarrhea, improving comfort during cancer treatment.
What could go wrong
This is a small, early-phase study with only 30 participants and no comparison group, so results may not be reliable or apply to everyone. The supplement is not a treatment for cancer itself.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

30 people

The number who actually took part.

Started

Jan 2023

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1、Age ≥ 18 years; 2、Patients with gastrointestinal tumors currently receiving chemotherapy with irinotecan or fluorouracil agents; 3、Experienced diarrhea after previous chemotherapy and recovered after treatment; 4、Experienced diarrhea again after this course of chemotherapy; 5、Adequate organ function. Exclusion Criteria： 1、Allergic to foods such as taro, rice, or carrots; 2、Diarrhea after previous chemotherapy not cured; 3、Patients unable to eat orally; 4、Patients with severe mental illness; 5、Patients who cannot cooperate well.

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Conditions

The condition(s) this trial relates to.

carcinoma of esophagus colon carcinoma colorectal cancer Esophageal Neoplasms gastric adenocarcinoma gastroesophageal adenocarcinoma gastroesophageal cancer gastroesophageal junction adenocarcinoma rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colon and rectal cancer Gastric adenocarcinoma or gastroesophageal junction adenocarcinoma or esophageal carcinoma

Contacts and locations

Locations

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, Dr., China

More trials for these conditions

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