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New drug cocktail targets Hard-to-Treat ovarian and uterine cancers

NCT ID NCT06107868

First seen Jan 05, 2026 · Last updated May 24, 2026 · Updated 22 times

Summary

This early-phase study tests a new investigational drug (RP-6306) combined with two standard chemotherapies (carboplatin and paclitaxel) in people with recurrent ovarian or uterine cancer that has a specific genetic change (TP53 mutation). The main goal is to find the safest dose and see if the combination can shrink tumors or slow disease progression. Only 6 participants are enrolled, and all have cancers that no longer respond to standard treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

Conditions

Explore the condition pages connected to this study.