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Pistachio power: daily snack may fight inflammation and boost muscle

NCT ID NCT06342024

Symptom relief Sponsor: Virginia Polytechnic Institute and State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether eating 1.5 ounces of pistachios every day for six months can lower inflammation and increase lean body mass in active adults aged 40 to 60. Participants will be randomly assigned to eat pistachios or avoid them while keeping their usual diet and exercise. Researchers will measure blood markers of inflammation and muscle health, as well as body composition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
pistachios
What this could lead to
If it works, this could show that eating pistachios is a simple way for active adults to lower inflammation and improve body composition.
What could go wrong
This is a small, early-stage study with no blinding, and results may not apply to everyone. The effect might be small or not meaningful for health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 144 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. women and men, 40 to 60 years of age 2. exercise three to five days a week for at least the past six months 3. non-smokers 4. not be on an active weight loss program at the start of the study or any time during the study 5. willing to maintain and not change their usual exercise habits 6. willing to consume pistachios as part of their diet (should they be randomized into the pistachio group) Exclusion Criteria: 1. unwilling to sign the informed consent document 2. not exercising regularly, three to five times per week for at least the past six months 3. physician states that they are not able to participate in the study 4. already consuming one or more ounces of pistachios several times a week 5. smoker 6. pregnant or lactating women 7. anyone who has a nut allergy

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Conditions

The condition(s) this trial relates to.

inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inflammatory response

Contacts and locations

Locations

  • Virginia Polytechnic Institute and State University

    Blacksburg, Virginia, 24061, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.