Chemo fog targets stomach cancer spread in new trial
NCT ID NCT07517419
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a procedure called PIPAC, which turns chemotherapy drugs into a mist and sprays them directly into the abdomen. It is for people with stomach cancer that has spread to the lining of the belly. The goal is to see if this approach is safe and can help control the disease. About 30 adults will take part.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2021
- Expected to finish
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Feb 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients age \>= 18, \<= 80 years old 2. Performance status (WHO) \<=2 3. Histologically evidenced synchronous PM of gastric adenocarcinoma cancer 4. Peritoneal Cancer Index (PCI) score \> 8, or \<=8 and patient not fit for cytoreductive surgery + hyperthermic intraperitoneal chemotherapy (CRS + HIPEC) 5. Patients with isolated ovarian metastasis could be included 6. White blood cells \>3.5000/mm3; neutrophils \> 1.500/mm3; platelets \>100,000/mm3 7. Creatinine \<1.5mg/dL and creatinine clearance \>60ml/min and serum total bilirubin \<2mg/dL 8. Ability to give written consent prior to commencement of treatment Exclusion Criteria: 1. Extraperitoneal metastases including liver metastases and malignant pleural effusion. The presence of suspicious retroperitoneal lymph nodes is not an exclusion criterium. 2. Patients with adenocarcinoma of Siewart I 3. Bowel obstruction, not tolerating oral diet 4. HER2+++ tumor with indicated for Trastuzumab therapy 5. Any laparotomy during 3 months before inclusion. (Laparoscopy is not an exclusion criterium) 6. Contraindicated to any drug contained in the chemotherapy regimen 7. Concomitant intraperitoneal chemotherapy, immunotherapy or target therapy 8. Active infectious (bacterial, viral) disease. Elevated CRP with no identified focus is not an exclusion criterium 9. Pregnancy or breastfeeding
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Chinese University of Hong Kong, Shatin, HK
Hong Kong, Hong Kong
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