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Can rewards and mindfulness help opioid patients stay on track?
NCT ID NCT04464421
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested two behavioral programs to help people with opioid use disorder take their medication as prescribed. One group could win gift cards when their urine tests showed they were taking their medicine. The other group had one-on-one sessions to set goals, find fun activities without substances, and learn mindfulness skills. The study included 48 adults starting treatment at an opioid clinic.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- behavioral interventions (contingency management and brief motivational interviewing plus mindfulness)
- What this could lead to
- If successful, these approaches could offer simple, non-drug ways to help people with opioid use disorder stay on their treatment medication.
- What could go wrong
- This was a very small pilot study with only 48 people, so results may not apply to everyone. The interventions are behavioral and may not work for all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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48 people
The number who actually took part.
- Started
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Aug 2020
- Finished
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Aug 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Present for an intake appointment at study site for treatment of opioid use disorder. * Eligible for receipt of buprenorphine-naloxone treatment (e.g. Suboxone, Bunavil, Zubsolv) as determined by clinic physicians * 18 years or older * Willing to be randomized to one of the two intervention arms * Ability to comprehend consent and intervention materials (approximately 8th-grade level).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Tennessee Health Science Center
Memphis, Tennessee, 38163, United States
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