Rare bone disease patient tries exercise therapy — early results promising?
NCT ID NCT07521150
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a structured physiotherapy and exercise program can improve pain, strength, balance, and quality of life in one person with melorheostosis, a rare bone condition. The patient will do exercises three times a week for eight weeks, along with education about their condition. Because it's just a single case, the findings are very preliminary and may not apply to others.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- structured exercise program and patient education
- What this could lead to
- If successful, this could suggest that physiotherapy helps manage symptoms of melorheostosis, a rare bone disease.
- What could go wrong
- This is a single-patient case report, so results may not apply to others. The study is very early and small, with no control group.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1 person
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with melorheostosis by a physician. * Voluntarily agreeing to participate in the study and providing written informed consent. * Being under physician follow-up for the disease. * Being 18 years of age or older. * Having the cognitive level, communication skills, and physical capacity to perform the planned exercise program. Exclusion Criteria: * Presence of additional systemic, rheumatologic, or metabolic diseases that could affect bone metabolism, other than melorheostosis. * Presence of cardiovascular, pulmonary, or neurological disease at a level that may restrict exercising. * History of surgical intervention or severe trauma within the last six months. * Presence of psychiatric or cognitive disorders that could interfere with evaluation and exercise applications. * Failure to continue the 8-week exercise program.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Yeditepe University
Istanbul, 34755, Turkey (Türkiye)
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