Could a simple mineral test predict ventilator needs in sepsis?
NCT ID NCT07739251
First seen Jul 31, 2026 · Last updated Jul 31, 2026
Summary
This study investigates whether low blood phosphate levels in patients with sepsis are linked to how long they need mechanical ventilation. Sepsis is a life-threatening condition where the body's response to infection damages its own organs, often requiring breathing support. The researchers will measure phosphate levels in 110 adult sepsis patients upon ICU admission and track the duration of their ventilator use, aiming to see if a simple blood test could help predict outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If a link is found, it could point to early phosphate monitoring as a way to identify high-risk sepsis patients and potentially shorten their time on a ventilator.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. The results may not apply to all sepsis patients, and other factors could influence the outcomes.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 110 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with sepsis or meeting the diagnostic criteria of septic shock
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with sepsis or meeting the diagnostic criteria of septic shock * Clinical criteria of septic shock * A patient with sepsis who, despite adequate fluid resuscitation, has: * A vasopressor requirement to maintain a mean arterial pressure (MAP) ≥ 65 mmHg, and * A serum lactate level \> 2 mmol/L (18 mg/dL) * Age more than 18 years old Exclusion Criteria: * \- Age less than 18 years. * ICU stay less than 24 hours. * Patients receiving renal replacement therapy before ICU admission. * Patients with known parathyroid disorders or metabolic bone disease. * Patients receiving phosphate supplements before ICU admission. * Patients receiving medications affecting phosphate levels, such as , insulin overdose, or chemotherapy. * Patients with diabetic ketoacidosis. * Patients with burns, major trauma, or postoperative ICU admission. * Pregnant patients. * Refusal to participate in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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- Can a computer model speed up sepsis blood tests?