Simple drug infusion may stop shivering during C-Sections
NCT ID NCT07663149
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether giving a continuous infusion of phenylephrine (a drug that raises blood pressure) can prevent shivering after spinal anesthesia in women having a C-section. About 108 non-laboring women will be randomly assigned to receive either the phenylephrine infusion or no infusion. The main goal is to see if fewer women shiver during the surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Phenylephrine
- What this could lead to
- If effective, this could offer a simple way to reduce shivering during C-sections, improving patient comfort and safety.
- What could go wrong
- This is a small, early-stage trial with 108 participants, so results may not apply to all patients. Phenylephrine can also cause side effects like high blood pressure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
108 people
The number who actually took part.
- Started
-
Apr 2026
- Finished
-
Jun 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 50 years
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Females aged 18-50 years. * Patients undergoing a Cesarean section procedure under spinal anesthesia. * Patients who are not in labor (non-labor). * Patients willing to participate in this study. Exclusion Criteria: * Patients with contraindications to phenylephrine. * Patients with allergies to the study medications. * Presence of fever (temperature \>37.5°C) or hypothermia (temperature \<35°C). * American Society of Anesthesiologists (ASA) score of III or higher. * Patients with a history of untreated thyroid disease. * Patients with a history of autonomic nervous system neuropathy. * Hypertension in pregnancy (or gestational hypertension). * Body Mass Index (BMI) greater than 35 kg/m².
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Shivering caused by spinal anesthesia are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
RSUP dr. Cipto Mangunkusumo
Jakarta Pusat, Jakarta Special Capital Region, 10430, Indonesia
More trials for these conditions
Other studies related to the condition(s) this trial covers.