Immune cells injected into spine take on deadly brain melanoma
NCT ID NCT07414979
First seen Feb 26, 2026 · Last updated Apr 29, 2026 · Updated 9 times
Summary
This early-phase trial tests a new approach for people with melanoma that has spread to the lining of the brain (leptomeningeal disease). Doctors will take a patient's own immune cells (CD8+ T cells), grow them in a lab, and inject them directly into the spinal fluid. The goal is to see if this treatment is safe and can control the disease. Only 8 participants with specific genetic markers (HLA-A2 or HLA-A24) will be enrolled.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The University of Texas M. D. Anderson Cancer Center
Houston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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