Immune cells injected into spine to fight brain cancer
NCT ID NCT07414979
First seen Feb 26, 2026 · Last updated Jun 23, 2026 · Updated 18 times
Summary
This early-phase trial tests whether immune cells (CD8+ T cells) given through a spinal tap are safe for people with melanoma that has spread to the lining of the brain. Only 8 participants will receive the treatment. The main goal is to check for side effects, not to cure the disease.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The University of Texas M. D. Anderson Cancer Center
Houston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CD8+ T cells (immune cells)
What this could lead to
If it works, this could point toward a new way to treat melanoma that has spread to the brain lining.
What could go wrong
This is a very early, small trial (8 people) focused on safety, not effectiveness. The treatment may not work or could cause serious side effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.