Can a simple throat device strengthen your swallow?
NCT ID NCT05708911
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a pharyngeal exerciser can increase the workload of swallowing muscles in healthy young and older adults. Researchers will use X-ray and pressure measurements to see changes in throat movement and muscle effort. The goal is to understand if such a device could eventually help people with swallowing disorders.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Pharyngeal exerciser (device)
- What this could lead to
- If successful, this could point toward a non-drug exercise device to help people with swallowing difficulties.
- What could go wrong
- This is a small, early study in healthy volunteers, not patients. It measures muscle activity, not actual improvement in swallowing problems.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2014
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy volunteers must be at least 18 years of age or older. Exclusion Criteria: * Subjects with cervical spine disorders. * Subjects with neurological disorders like dementia, cerebrovascular diseases other than Parkinson's Disease * Subjects with carotid artery bruit or carotid vascular disorders. * Subjects suffering from muscle diseases like muscular dystrophies, myopathies. * Subjects with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders. * Subjects with any current esophageal symptoms like heartburn, dysphagia, chest pain or regurgitation. * Subjects cannot have previous head or neck surgery or radiation. * Subjects unable to tolerate nasal intubation. * Subjects with significant bleeding disorders for whom nasal intubation has been deemed contraindicated. * Subjects with a known upper airway or esophageal obstruction preventing the passage of the manometry probe. * Subjects with autonomic dysfunction. * Subjects having a history of allergy to lidocaine and barium. * Subjects who are pregnant or lactating. * Subjects who have advanced medical disorders (e.g.: chronic obstructive pulmonary disease (COPD), congestive heart failure, cirrhosis, cancer, chronic renal failure, etc.). * Subjects who are medically unstable.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53086, United States
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Other studies related to the condition(s) this trial covers.
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- A gentle vibration could prompt safer swallowing in Parkinson's
- Can gentle air puffs to the throat reboot swallowing after stroke?