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New drug combo targets Hard-to-Treat cancers in early trial

NCT ID NCT05233436

First seen Feb 21, 2026 · Last updated Jun 12, 2026 · Updated 21 times

Summary

This early-phase study tested an experimental drug (PF-07265028) alone or with another drug (sasanlimab) in 21 people with advanced solid tumors like lung, stomach, or bladder cancer. The goal was to find the safest dose and see if the drugs shrink tumors. The study was stopped early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • HonorHealth Research Institute

    Scottsdale, Arizona, 85258, United States

  • HonorHealth Scottsdale Shea Medical Center

    Scottsdale, Arizona, 85260, United States

  • Mary Crowley Cancer Research

    Dallas, Texas, 75230, United States

  • National Cancer Center Hospital East

    Kashiwa, Chiba, 277-8577, Japan

  • START Midwest

    Grand Rapids, Michigan, 49546, United States

  • South Texas Accelerated Research Therapeutics, LLC

    San Antonio, Texas, 78229, United States

  • The Cancer Institute Hospital of JFCR

    Koto, Tokyo, 135-8550, Japan

  • University of Iowa

    Iowa City, Iowa, 52242, United States

Conditions

The condition(s) this trial relates to.

gastric neoplasm gastroesophageal cancer lung neoplasm Neoplasm Metastasis non-small cell lung carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.