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PET scans may sharpen staging for rare lymphoma

NCT ID NCT04600804

Knowledge-focused Sponsor: Fondazione Italiana Linfomi - ETS Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study examined whether PET scans can help doctors better stage mantle cell lymphoma and predict how patients will fare, compared to standard CT scans and bone marrow biopsies. Researchers analyzed data from 200 patients who had already completed a clinical trial. The goal was to see if PET results could improve prognostic models and guide future studies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better ways to stage mantle cell lymphoma and predict patient outcomes, potentially improving future treatment planning.
What could go wrong
This is a retrospective imaging study, not a treatment trial. It only looks at existing data, so it cannot prove that using PET scans improves patient survival or outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

200 people

The number who actually took part.

Started

Oct 2020

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

A total of 300 patients have been enrolled in the MCL0208 trial. We expect to analyze the PETs, clinical and biological data of about 200 patients enrolled in the MCL0208 trial who performed the PET exams within the clinical trial and who consent to the present study: all PETs available at each center participating in this study will be collected and analyzed.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Enrollment of the patient in the MCL0208 clinical trial documented by the signature of the study informed consent; * Patient's treatment in one of the centers that participated in the MCL0208 trial and that has joined the MCL0208-PET study as well; * Evidence of signed informed consent for the MCL0208-PET study.

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Conditions

The condition(s) this trial relates to.

mantle cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mantle cell lymphoma

Contacts and locations

Locations

  • Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI)

    Trieste, Italy

  • Div. di Ematologia IRCCS Policlinico S. Matteo di Pavia

    Pavia, Lombardy, 27100, Italy

  • Divisione di Ematologia A.O. Ospedali Riuniti Villa Sofia-Cervello

    Palermo, Sicily, 90146, Italy

  • Divisione di Ematologia e T.M.O. - Ospedale Centrale di Bolzano

    Bolzano, Trentino-Alto Adige, 39100, Italy

  • Ematologia - Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.)

    Meldola, 47014, Italy

  • Ematologia ASST MONZA Ospedale S. Gerardo

    Monza, Lombardy, 20900, Italy

  • Ematologia ASST Spedali Civili di Brescia

    Brescia, Lombardy, 25123, Italy

  • Ematologia Azienda Unitа Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova

    Reggio Emilia, Emilia-Romagna, 42123, Italy

  • Ematologia Ospedale Maggiore Policlinico - Fondazione IRCCS Ca Granda

    Milan, Lombardy, 20122, Italy

  • Ematologia Ospedale Policlinico San Martino S.S.R.L. - IRCCS per l Oncologia

    Genoa, Liguria, 16132, Italy

  • Ematologia Ospedale Vito Fazzi

    Lecce, Apulia, 73100, Italy

  • Ematologia Universitaria A.O.U. Citta della Salute e della Scienza di Torino

    Turin, Piedmont, 10126, Italy

  • Ematologia Universitа Cattolica S. Cuore

    Rome, Lazio, 00168, Italy

  • Instituto Português de Oncologia de Lisboa

    Lisbon, Portugal

  • S.C di Ematologia Ospedale Ca Foncello

    Treviso, Veneto, 31100, Italy

  • S.C. Ematologia A.O. SS. Antonio e Biagio e Cesare Arrigo

    Alessandria, Piedmont, 15121, Italy

  • S.C. Ematologia Azienda Ospedali Riuniti Papardo-Piemonte

    Messina, Sicily, 98158, Italy

  • S.C. Oncoematologia A.O. S. Maria di Terni

    Terni, Umbria, 05100, Italy

  • S.C. di Ematologia e Trapianto di Midollo Osseo A.O. S. Croce e Carle

    Cuneo, Piedmont, 12100, Italy

  • S.C.Ematologia A.O.U. Citta della Salute e della Scienza di Torino

    Turin, Piedmont, 10126, Italy

  • S.O.C. Oncologia Medica A Centro Riferimento Oncologico

    Aviano, Friuli Venezia Giulia, 33081, Italy

  • SC Ematologia ASST Grande Ospedale Metropolitano Niguarda

    Milan, Lombardy, 20162, Italy

  • SC Ematologia e CTMO Ospedale Businco

    Cagliari, Sardinia, 09121, Italy

  • SCDU Ematologia AOU Maggiore della Caritа di Novara

    Novara, Piedmont, 28100, Italy

  • SOC Clinica Ematologica Azienda Sanitaria Universitaria Friuli Centrale (ASU FC)

    Udine, Friuli Venezia Giulia, 33100, Italy

  • U.O. Clinica Ematologica Ospedale Policlinico San Martino S.S.R.L. - IRCCS per l Oncologia

    Genoa, Liguria, 16132, Italy

  • U.O. Ematologia - AOU Pisana

    Pisa, Italy

  • U.O. Ematologia AOU Integrata di Verona

    Verona, Veneto, 37134, Italy

  • U.O. Ematologia Istituto Clinico Humanitas

    Rozzano, Lombardy, 20089, Italy

  • U.O. di Ematologia Ospedale degli Infermi di Rimini

    Rimini, Emilia-Romagna, 47923, Italy

  • U.O.C Ematologia e Trapianto A.O. C. Panico

    Tricase, Apulia, 73039, Italy

  • U.O.Ematologia Ospedale Guglielmo da Saliceto

    Piacenza, Emilia-Romagna, 29121, Italy

  • Unità Linfomi - Dipartimento Oncoematologia - Istituto Scientifico San Raffaele

    Milan, Milan, Italy

  • Unitа funzionale di Ematologia Azienda Ospedaliera Universitaria Careggi

    Florence, Tuscany, 50141, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.