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Brain training shows promise for easing depression and anhedonia

NCT ID NCT05869708

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 29 times

Summary

This study tested a personalized brain-training method called PRISM neurofeedback in 19 adults with major depression and anhedonia (loss of pleasure). Participants were randomly assigned to receive either real or sham (fake) training. The goal was to see if the therapy is safe and can reduce symptoms, and to find simple ways for clinics to match the therapy to each person. The results help guide how to combine this brain training with standard depression care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • McLean Hospital

    Belmont, Massachusetts, 02478, United States

Conditions

Explore the condition pages connected to this study.