Smart tool aims to predict safe blood pressure for each surgery patient
NCT ID NCT07156474
First seen Jun 25, 2026 · Last updated Aug 07, 2026 · Updated 3 times
Summary
This study looks at data from over 44,000 patients to find the best way to manage blood pressure during surgery and prevent kidney damage. Researchers will build a computer model that predicts a safe blood pressure target for each individual patient. The goal is to give doctors a personalized guide to keep kidneys healthy during an operation.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a personalized tool that helps doctors set safe blood pressure targets during surgery, reducing the risk of kidney damage.
- What could go wrong
- This is an observational study using past data, so it cannot prove cause and effect. The machine learning model may not work for all patients or in real-time during surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 44,504 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All non-cardiac surgery data from INSPIRE database and all non-cardiac surgery data from 2013-2024 in Zhongda Hospital Southeast University, 2016-2024 in Nanjing First Hospital and 2013-2023 in Anhui Medical University Affiliated First Hospital were selected.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients undergoing non-cardiac surgery 2. Access to intraoperatively available invasive/noninvasive blood pressure monitoring data Exclusion Criteria: 1. Patients for Age \< 18 yr 2. Patients without preoperative or postoperative creatinine records 3. Patients undergoing urinary surgeries 4. Patients with chronic kidney injury before surgery 5. ASA grade \> 5 class 6. Anesthesia duration \< 60 min 7. Patients for non-available lowest blood pressure data during surgery 8. Hemodynamic records loss more than 25% of the total anesthesia duration 9. Patients for categorical variables records missing
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Zhongda Hospital Southeast University
Nanjing, Jiangsu Provincce, 210000, China
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