New mapping tech aims to stop AFib in its tracks
NCT ID NCT07358611
First seen Jun 25, 2026 · Last updated Jul 09, 2026 · Updated 3 times
Summary
This pilot study tests whether using a noninvasive global mapping system to guide catheter ablation can improve outcomes for people with persistent atrial fibrillation. Thirty participants will receive standard pulmonary vein isolation plus personalized ablation of up to three additional heart regions identified by the mapping system. Researchers will track how often the heart returns to normal rhythm during the procedure and how many patients remain free of arrhythmia for a year.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- catheter ablation guided by noninvasive global mapping
- What this could lead to
- If successful, this personalized ablation approach could reduce the chance of atrial fibrillation coming back after treatment.
- What could go wrong
- This is a small pilot study with only 30 participants, so results may not apply to everyone. The procedure carries standard risks of catheter ablation, such as bleeding or heart rhythm issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Ablation-naïve patients with: 1. Persistent AF planned for catheter ablation plus 2. Left atrial enlargement (LA diameter ≥45 mm or LA volume index ≥35ml/m2 or LA area ≥20 cm2) Exclusion Criteria: * Previous cardiac ablation * Age \<18 years * Pregnancy or lactation * Previous stroke/TIA * Severe left ventricular dysfunction (LVEF \<35%) * Renal failure (GFR \<30 ml/min) * Dermal disease or hypersensitivity predisposing for skin irritation or exanthema
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Clinic, University of Barcelona
RECRUITINGBarcelona, 08036, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a checklist and heart monitor stop repeat strokes?
- Two ways to quiet a racing heart: trial pits hybrid ablation against standard catheter treatment
- Can a breathing workout and walks help dialysis patients with irregular heartbeats?
- Zapping the ear: a new way to stop Post-Surgery heart rhythm problems?
- Can a new mapping and ablation system fix recurring atrial fibrillation?