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New knee system tracked in 700-Patient study

NCT ID NCT03495232

First seen Dec 18, 2025 · Last updated Jun 19, 2026 · Updated 28 times

Summary

This study follows 700 people receiving a Persona total knee replacement to see how well the artificial joint works over time. Researchers will measure pain, function, and quality of life using patient questionnaires, and track how long the implant lasts (up to 10 years). The goal is to understand the real-world performance and safety of this knee system.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Copenhagen University Hospital, Hvidovre

    Copenhagen, Denmark

  • Institute Locomoteur de L'Ouest

    Saint-Grégoire, 35760, France

  • Ortopedic Clinic, Motala Specialist Care Capio AB

    Motala, Sweden

  • St Olavs Hospital

    Trondheim, Norway

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Zimmer Biomet Persona total knee system (artificial knee joint)

What this could lead to

If successful, this could confirm that the Persona knee system provides good pain relief and function for at least 10 years after surgery.

What could go wrong

This is an observational study, not a randomized trial comparing treatments. Results may not apply to all patients, and some may still experience complications or need revision surgery.

Conditions

The condition(s) this trial relates to.

arthropathy osteoarthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.