New knee system aims to give patients a second chance at Pain-Free movement
NCT ID NCT04821154
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 24 times
Summary
This study is testing a new knee replacement system called Persona Revision Knee System in 380 adults who need a second knee replacement (revision). The goal is to see if it improves pain, stability, and range of motion over two years. The study is observational with follow-up visits, and it will also track any side effects or need for further surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Locations
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Advanced Orthopaedic Specialists
RECRUITINGFayetteville, Arkansas, 72703, United States
Contact
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Arthroplasty Foundation Inc.
COMPLETEDLouisville, Kentucky, 40220, United States
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Ascension Providence Rochester Hospital
RECRUITINGRochester, Michigan, 48307, United States
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Bowen Hefley Orthopedics
RECRUITINGLittle Rock, Arkansas, 72205, United States
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Community Foundation Medical Group
WITHDRAWNFresno, California, 93720, United States
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Cornerstone Orthopaedics & Sports Medicine
COMPLETEDSuperior, Colorado, 80027, United States
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Jeff Yergler, LLC
RECRUITINGGranger, Indiana, 46530, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Michigan Orthopaedic Surgeons, PLLC
ACTIVE_NOT_RECRUITINGSouthfield, Michigan, 48076, United States
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Orthopaedic Associates, Inc.
COMPLETEDEvansville, Indiana, 47710, United States
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Orthopaedic Research Institute of New Jersey
RECRUITINGChester, New Jersey, 07390, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Orthopedic Surgeons of Wisconsin, SC
WITHDRAWNWauwatosa, Wisconsin, 53222, United States
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Penn Medicine/ Lancaster General Health
COMPLETEDLancaster, Pennsylvania, 17602, United States
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ROC Orthopedics
COMPLETEDOregon City, Oregon, 97045, United States
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TRIA Orthopaedic Center Research Institute
COMPLETEDBloomington, Minnesota, 55431, United States
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The Cleveland Clinic Foundation
RECRUITINGCleveland, Ohio, 44195, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
Contact
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Thomas Aleto MD, PC
WITHDRAWNColumbia, Missouri, 65201, United States
Conditions
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