New flap technique aims to restore mouth function after cancer surgery
NCT ID NCT07590427
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests a surgical flap taken from the jawbone lining to rebuild small-to-medium sized defects in the floor of the mouth, often after cancer removal. Twenty adults who need this reconstruction will receive the flap procedure. Researchers will measure pain, speech, swallowing, and complications to see if the technique is reliable and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- surgical procedure: lateral periosteal-muscular flap
- What this could lead to
- If successful, this flap could offer a reliable, simpler option for rebuilding small-to-medium mouth defects after cancer surgery, potentially improving speech and swallowing.
- What could go wrong
- This is a very small, early-stage trial with only 20 participants. The procedure may not work for everyone, and risks include infection, flap failure, or poor healing.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients requiring reconstruction of small and medium sized FOM defects. Exclusion Criteria: * Previous neck dissection. * Previous radiotherapy in the maxillofacial region. * Uncontrolled diseases that may contraindicate the surgery
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt
Alexandria, Azarita, 00203, Egypt