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Gum disease study seeks clues in immune system to stop bone destruction

NCT ID NCT04831060

First seen Jan 21, 2026 · Last updated Jun 06, 2026 · Updated 21 times

Summary

This study aims to understand how the immune system causes bone destruction in gum disease (periodontitis) and implant-related gum disease (peri-implantitis). Researchers will collect samples like plaque, saliva, and gum fluid from 219 adults with severe gum disease and compare them to healthy individuals. The goal is to find specific molecules that could lead to better prevention, screening, and treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dentistry department- Rothschild hospital

    RECRUITING

    Paris, 75012, France

    Contact Email: •••••@•••••

  • Service d'odontologie, hôpital Charles Foix

    RECRUITING

    Ivry-sur-Seine, 94200, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

diabetes mellitus Inflammation Peri-Implantitis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.