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Scientists hunt for clues to stop gum disease bone destruction

NCT ID NCT04831060

First seen Jan 21, 2026 · Last updated Apr 30, 2026 · Updated 15 times

Summary

This study aims to understand the immune and inflammatory processes that lead to bone destruction in gum disease (periodontitis) and infections around dental implants (peri-implantitis). Researchers will collect plaque, saliva, and gum fluid from 219 adults with advanced gum disease and compare them to healthy individuals. The goal is to identify specific molecules that could serve as biomarkers for disease activity or targets for future treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dentistry department- Rothschild hospital

    RECRUITING

    Paris, 75012, France

    Contact Email: •••••@•••••

  • Service d'odontologie, hôpital Charles Foix

    RECRUITING

    Ivry-sur-Seine, 94200, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.