Scientists probe hidden oxygen changes during breast cancer surgery
NCT ID NCT03797482
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at how oxygen levels in breast tumors change during surgery and how those changes affect gene activity. Researchers will take small tumor samples at three points during surgery from 500 women with breast cancer. The goal is to understand the body's response to surgery, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal how surgery affects breast cancer cells at a genetic level, potentially guiding future treatments to improve outcomes.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly benefit participants and may not lead to any new therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2017
- Expected to finish
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Nov 2025
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Women diagnosed with breast cancer at outpatient clinic
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Clinically diagnosis of breast cancer (by FNAC or Biopsy) 2. Not received any chemotherapy or surgical intervention except core biopsy. 3. Planed for Breast cancer surgery 4. Willing to give consent for the study Exclusion Criteria: 1. Clinically diagnosis of Metastatic breast cancer 2. Received any anticancer therapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tata Memorial Center
RECRUITINGMumbai, Maharashtra, 400012, India
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