MS Patients' Self-Awareness of movement under the microscope
NCT ID NCT07175792
First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times
Summary
This study compares how accurately people with multiple sclerosis (MS) and healthy controls perceive changes in their own walking and sit-to-stand performance. Researchers will measure how well participants detect natural variations in their movement speed and smoothness. The goal is to uncover specific perception deficits in MS that could guide future personalized therapies.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify specific perception deficits in MS and help design tailored interventions to improve motor performance awareness.
- What could go wrong
- This is an observational study with no treatment, so it cannot directly improve health. Results may not lead to clear clinical changes or apply to all MS patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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72 people
The number who actually took part.
- Started
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Dec 2024
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
44 PwMS and 44 healthy controls will be recruited from the Flemish MS rehabilitation centers in Melsbroek (NMSC) and Pelt (Noorderhart RMSC), and as well from the REVAL research center in UHasselt. No economical compensation will be provided. We will search age and sex-matching healthy controls, considering a 5-year range per subject. After giving informed consent, demographics of age and gender, height and weight, years of education, as well as MS-related information such as EDSS, type of MS, use of assistive device for walking in daily life, and year of diagnosis, will be collected and provided by the centers or via self-report. The participants will be instructed to keep their normal routine but to avoid extraneous physical activity at least 24 hours before the data collection session.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * age between 18 and 70 years old * ability to walk for 6 minutes without rest and without the need of a walking aid * ability to repeatedly perform the sit to stand transitions on a standard chair (43cm seat height) without hand support For People with Multiple Sclerosis group * a diagnosis of MS (2017 revisions of the McDonalds criteria) * no disease relapses \>1 month preceding the start of the study Exclusion Criteria: * cognitive impairment hindering understanding of study instructions * ongoing or suspected pregnancy * musculoskeletal disorders in the lower limbs * cardiovascular red flags for exercise (screened with Physical Activity Readines Questionnaire) * other diagnosis for neurological or metabolic disease limiting the full execution of the tests
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Nationaal MS-Centrum Melsbroek
Steenokkerzeel, Belgium, 1820, Belgium
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Noorderhart Revalidatie & MS
Overpelt, Belgium, 3900, Belgium
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REVAL
Diepenbeek, Belgium, 3590, Belgium
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